Opportunities for cellular rejuvenation in Alzheimer’s disease: how epigenetic reprogramming and chaperone-mediated autophagy are enabling next generation therapeutic approaches. Rosenzweig-Lipson, S. The Journal for Prevention of Alzheimer’s Disease. 2023 October 24; 10, 661–668.
Our Science
Publications
Scientists at Life Biosciences regularly publish articles in peer-reviewed journals and publications to inform the scientific community of our research and to contribute to the advancement of research in the field of aging.
Loss of epigenetic information as a cause of mammalian aging. Yang J, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Ching Chew Y, Guo W, Yang X, Maybury-Lewis S, Tian X, Ross JM, Coppotelli G, Meer MV, Rogers-Hammond R, Vera DL, Lu YR, Pippin JW, Creswell ML, Dou Z, Xu C, Mitchell SJ, Das A, O’Connell BL, Thakur S, Kane AE, Su Q, Mohri Y, Nishimura EK, Schaevitz L, Garg N, Balta AM, Rego MA, Gregory-Ksander M, Jakobs TC, Zhong L, Wakimoto H, El Andari J, Grimm D, Mostoslavsky R, Wagers AJ, Tsubota K, Bonasera SJ, Palmeira CM, Seidman JG, Seidman CE, Wolf NS, Kreiling JA, Sedivy JM, Murphy GF, Green RE, Garcia BA, Berger SL, Oberdoerffer P, Shankland SJ, Gladyshev VN, Ksander BR, Pfenning AR, Rajman LA, Sinclair DA. Cell. 2023 January 19; 186;2, 305-326.
Reprogramming to recover youthful epigenetic information and restore vision. Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang J-H, Zhou S, Hoffmann EM, Karg MM, Schultz MB, Kane AE, Davidsohn N, Korobkina E, Chwalek K, Rajman LA, Church GM, Hochedlinger K, Gladyshev VN, Horvath S, Levine ME, Gregory-Ksander MS, Ksander BR, He Z, Sinclair DA. Nature. 2020 December 2; 588, 124–129.
In vivo amelioration of age-associated hallmarks by partial reprogramming. Ocampo A, Reddy P, Martinez-Redondo P, Platero-Luengo A, Hatanaka F, Hishida T, Li M, Lam D, Kurita M, Beyret E, Araoka T, Vazquez-Ferrer E, Donoso D, Roman JL, Xu J, Esteban CR, Nuñez G, Delicado EN, Campistol JM, Guillen I, Guillen P, Belmonte JCI. Cell. 2016 December 15; 167:7, 1719-1733.
This page contains links to websites or publications owned and operated by third parties (“Websites”). If you use these links, you leave our website. These links are provided for your information and convenience only and are not an endorsement by Life Biosciences. Life Biosciences has no control over the content of any linked Websites and is not responsible for its content or availability. Access to linked Websites may require permissions from and/or payments to copyright holders. Life Biosciences therefore makes no warranties or representations, express or implied, about any linked Websites, the third parties they are owned and operated by, or the information contained on them.